고객센터 > 산소관련자료 > 수소가스의 실험 논문입니다.
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작성일 : 13-09-20 20:24
수소가스의 실험 논문입니다.
 글쓴이 : 관리자
조회 : 5,071  
Protective Effect of Hydrogen Gas Therapy After Germinal Matrix Hemorrhage in Neonatal Rats
 
Abstract
 
Background:
 
Germinal matrix hemorrhage (GMH) is a neurological disease of very low birth weight premature infants leading to post-hemorrhagic hydrocephalus, cerebral palsy, and mental retardation. Hydrogen (H2) is a potent antioxidant shown to selectively reverse cytotoxic oxygen-radical injury in the brain. This study investigated the therapeutic effect of hydrogen gas after neonatal GMH injury.
 
Methods:
 
Neonatal rats underwent stereotaxic infusion of clostridial collagenase into the right germinal matrix brain region. Cognitive function was assessed at 3 weeks, and then sensorimotor function, cerebral, cardiac and splenic growths were measured 1 week thereafter.
 
Results:
 
Hydrogen gas inhalation markedly suppressed mental retardation and cerebral palsy outcomes in rats at the juvenile developmental stage. The administration of H2 gas, early after neonatal GMH, also normalized the brain atrophy, splenomegaly and cardiac hypertrophy 1 month after injury.
 
Conclusion:
 
This study supports the role of cytotoxic oxygen-radical injury in early neonatal GMH. Hydrogen gas inhalation is an effective strategy to help protect the infant brain from the post-hemorrhagic consequences of brain atrophy, mental retardation and cerebral palsy. Further studies are necessary to determine the mechanistic basis of these protective effects.
 

관리자 13-09-20 20:45
답변  
신생아 쥐의 Germinal Matrix Hemorrhage 이후의 수소가스의 보호효과에 대한 논문의 간략한 자료입니다.
Webb 23-02-10 17:37
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Lisa 23-03-07 09:51
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Lisa 23-06-07 12:25
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Total 22
번호 제   목 글쓴이 날짜 조회
공지 MIT 제공 간단한 산소호흡기( Ventilator) 관리자 07-29 1319
22 소아 근육병의 진단과 치료 서울대학교 의과대학 소아과학교실 … 관리자 03-17 721
21 성인형 당원축적근육병 1예 서울대학교 의과대학 신경과학교실1 … 관리자 03-17 1275
20 미요시근육병 환자에서 밝혀진 Dysferlin 유전자 돌연변이 (1) 관리자 03-17 946
19 MIT 제공 간단한 산소호흡기( Ventilator) 관리자 07-29 1319
18 토끼의 척수허혈 재관류 손상에 대한 수소가스의 긍정적 효과에 … (2) 관리자 04-11 3840
17 수소가스와 염증과의 관계를 증명한 논문입니다. (1) 관리자 04-11 4282
16 Inhalation of hydrogen gas attenuates cisplatin-induced otot… (2) 관리자 10-14 3514
15 수소가스의 실험 논문입니다. (4) 관리자 09-20 5072
14 수소가스 실험 및 결과에 관한 자료입니다. (2) 관리자 09-20 6957
13 건강과 질병에 관하여-4 관리자 03-13 3700
12 건강과 질병에 관하여-3 관리자 03-12 4111
11 건강과 질병에 관하여-2 관리자 03-12 3450
10 건강과 질병에 관하여, 관리자 03-12 3080
9 방마다 맞는 色있다 관리자 09-04 3140
8 산소의 효과(출처: 맑은 숲 한의원) 관리자 09-04 4095
7 산소의 부족(출처-맑은 숲 한의원) 관리자 09-04 3392
6 항산화 식품, 활성산소 제거요법 관리자 09-04 4269
5 산소와 암 관리자 09-04 3209
4 산소 부족이 유발하는 질병 관리자 09-04 9283
3 산소가 공급되면 이러한 분에게 특히 좋습니다. 관리자 09-04 3097
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